He started in small roles as extra in the works in which his father and brother worked. He began his official acting career at the age of 13 in the TV drama Hachidai Shogun Yoshimune (1995). With over 100 credits to his name, Oguri has an extensive Japanese filmography, which includes Lupin the 3rd, Crows Zero and Gintama. He directed his first film in 2010, Surely Someday, a drama in which he had a cameo role. Oguri will make his Hollywood debut in Godzilla vs. Kong, to be released in 2020. As a voice actor, in 2005, he lent his voice in Fullmetal Alchemist the Movie: Conqueror of Shamballa as Alfons Heiderich, as well as other characters in other series.